Drug Interactions With Amphetamine and Dextroamphetamine (Cont.)

Amphetamine and Dextroamphetamine Interactions Explained

 
Acetazolamide (Diamox)
Taking amphetamine and dextroamphetamine and acetazolamide together can increase the amount of amphetamine and dextroamphetamine in the blood, resulting in possible side effects. Your healthcare provider may need to decrease your dose of amphetamine and dextroamphetamine.
 
Ammonium Chloride
Taking amphetamine and dextroamphetamine and ammonium chloride together can decrease the amount of amphetamine and dextroamphetamine in the blood, perhaps making amphetamine and dextroamphetamine less effective. Your healthcare provider may need to increase your dose of amphetamine and dextroamphetamine.
 
Certain Antacids
Taking amphetamine and dextroamphetamine with very high doses of certain antacids (such as calcium carbonate) can increase the amount of amphetamine and dextroamphetamine in the blood, resulting in possible side effects. This is probably not a problem with occasional use of antacids. Your healthcare provider may need to adjust your dose of these medications.
 
Certain Sleep Medications
Taking amphetamine and dextroamphetamine with certain sleep medications, such as diphenhydramine, can decrease the effectiveness of the sleep aid. Your healthcare provider may need to adjust your dose of these medications.
 
Chlorpromazine (Thorazine)
Taking amphetamine and dextroamphetamine and chlorpromazine together can change the way the brain reacts to amphetamine and dextroamphetamine, making amphetamine and dextroamphetamine less effective. Your healthcare provider may need to adjust your dose of these medications.
 
Ethosuximide (Zarontin)
Taking amphetamine and dextroamphetamine and ethosuximide together can cause ethosuximide to be absorbed in the body more slowly, perhaps making it less effective. Your healthcare provider may need to adjust your dose of these drugs.
(Drug Interactions With Amphetamine and Dextroamphetamine Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;