Drug Interactions With Eszopiclone (Cont.)

 
Nevirapine (Viramune)
Taking eszopiclone with nevirapine can decrease the level of eszopiclone in your blood, perhaps making it less effective. Your healthcare provider may need to adjust your dose of these medications.
 
Nicardipine (Cardene)
Taking eszopiclone with nicardipine can increase the level of eszopiclone in the blood, increasing your chance of side effects. Talk to your healthcare provider before taking these two medications together.
 
Olanzapine (Zyprexa, Symbyax)
Taking eszopiclone with olanzapine may have an effect on your mental functioning. Talk to your healthcare provider before taking these two medications together.
 
Protease Inhibitors
Taking eszopiclone with protease inhibitors can increase the level of eszopiclone in the blood, increasing your chance of developing side effects. Talk to your healthcare provider before taking these medications together.
 
Rifamycin Antibiotics
Taking eszopiclone with rifamycin antibiotics can decrease the level of eszopiclone in your blood, perhaps making it less effective. Your healthcare provider may need to adjust your dose of these medications.
 

Final Thoughts on Drug Interactions With Eszopiclone

It is possible that not all eszopiclone drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific drug interactions that may apply to your situation.
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;