Sleep Home > Amphetamine and Dextroamphetamine

How Does This Medication Work?

Amphetamine and dextroamphetamine is a stimulant, although it can have the opposite effects from what would be expected of a stimulant. While stimulants (like caffeine) can cause hyperactivity, when used at the proper doses for ADHD, amphetamine and dextroamphetamine has a calming effect.
The exact way in which the drug produces a calming effect is not known; however, it is known that amphetamine and dextroamphetamine affects chemicals in the brain. In general, this medication is used at higher, more stimulating doses when used for narcolepsy.

When and How to Take It

Some general considerations to keep in mind when taking amphetamine and dextroamphetamine include the following:
  • Amphetamine and dextroamphetamine comes in tablet form. It is usually taken by mouth twice daily, although some people (especially those using it for narcolepsy) will need to take it more often.
  • You can take this medicine with or without food.
  • For amphetamine and dextroamphetamine to work properly, it must be taken as prescribed. The medication will not work if you stop taking it.

Dosing Information

The dose of amphetamine and dextroamphetamine your healthcare provider recommends will vary, depending on a number of factors, including:
  • Your age
  • Other narcolepsy or ADHD medications you have tried
  • Other medical conditions you may have
  • Other medications you may be currently taking.
As with any medication, do not adjust your dose unless your healthcare provider specifically tells you to do so.
(Click Amphetamine and Dextroamphetamine Dosing for more information.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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