As mentioned, people who are taking prescribed doses of methylphenidate for legitimate medical purposes do not usually need to worry about methylphenidate withdrawal. However, if you have been taking very large doses of the drug, you may want to talk to your healthcare provider. He or she may recommend medications to help with withdrawal symptoms (such as antidepressants) and may be able to help with addiction or dependence problems. If you have been taking high doses of methylphenidate, slowly decreasing the amount taken each day can help prevent withdrawal symptoms.