Nuvigil Drug Interactions

Propranolol (Inderal, Inderal LA)
Taking propranolol with Nuvigil can increase the level of propranolol in your blood, possibly increasing the chance of side effects. Check with your healthcare provider before taking these two medications together.
 
Rifamycin Antibiotics
Rifamycin antibiotics may decrease the level of Nuvigil in your blood, perhaps making it less effective. Contact your healthcare provider if you notice that Nuvigil seems to be less effective since starting a rifamycin antibiotic.
 
Seizure Medications
Check with your healthcare provider before taking Nuvigil with any seizure medications. Some seizure medications may decrease the level of Nuvigil in your blood, and Nuvigil may increase the level of some seizure medications in your blood.
 
Some Protease Inhibitors
Some protease inhibitors may increase the level of Nuvigil in your blood, possibly increasing your risk of Nuvigil side effects. Check with your healthcare provider before taking Nuvigil with a protease inhibitor.
 
Tricyclic Antidepressants
Combining a tricyclic antidepressant with Nuvigil may increase the level of the antidepressant in your blood, possibly increasing your risk of side effects. Your healthcare provider may need to lower the dose of your tricyclic antidepressant to prevent this interaction from occurring.
 
Warfarin (Coumadin, Jantoven)
Nuvigil may interact with warfarin. Your healthcare provider may need to monitor you more closely and adjust your warfarin dosage as necessary, especially when you start or stop taking Nuvigil.
 

Final Thoughts on Nuvigil Drug Interactions

It is possible that not every drug interaction was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the Nuvigil drug interactions that may apply to you.
 

Nuvigil Drug Information

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