Drug Interactions With Valerian Root

Alcohol, antidepressants, and narcotics are among the medications that may cause negative interactions with valerian root. Drug interactions such as these can increase your risk of side effects, including drowsiness, confusion, or difficulty breathing. To avoid these complications, talk to your healthcare provider prior to taking the supplement about any potential drug interactions with valerian root that may apply to you.

 

Drug Interactions With Valerian Root: An Overview

Even though valerian root is a natural product, it can potentially interact with several medicines. Some of the medicines that may lead to drug interactions with valerian root include:
 
 
 
  • Barbiturates, such as:
 
    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)
 
  • Benzodiazepines, such as:
 
 
  • Narcotics or opiates, such as:
 
    • Morphine (MSIR®)
    • Oxycodone (OxyContin®)
    • Hydrocodone (Lortab®, Vicodin®)
 
  • Other sleep medications.
 
(Drug Interactions With Valerian Root Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;