Zolpidem Oral Spray
You should talk with your healthcare provider prior to taking this medication if you have:
- Sleep apnea or other types of respiratory disease, such as emphysema or COPD
- Liver disease or liver failure, including cirrhosis
- Any allergies, including allergies to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Zolpimist and Pregnancy)
- Breastfeeding (see Zolpimist and Breastfeeding).
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Zolpidem Oral Spray to learn more, including information on who should not take the drug.)
Zolpidem oral spray is part of a class of medications called sedative/hypnotics, which are known more commonly as sleep medicines. It is thought that the spray works by binding to certain receptors in the brain known as benzodiazepine receptors. It should be noted that zolpidem oral spray is not a benzodiazepine drug and is not chemically related to benzodiazepines, even though it binds to the same receptors.
Studies have shown that zolpidem oral spray helps people fall asleep faster, stay asleep longer, and wake up less frequently, compared to a placebo spray (with no active ingredients). Studies have also shown that zolpidem oral spray (at the recommended dosage) is unlikely to cause a "hangover" effect the next day and is unlikely to cause rebound insomnia (a worsening of insomnia once the medication is stopped).
Studies of zolpidem oral spray have been relatively short (a few weeks in duration), and it is not clear if this medication is effective when used for more than 35 days.