Drug Interactions With Zolpidem (Cont.)

 
Sertraline (Zoloft)
When Zoloft and zolpidem are used together, the amount of zolpidem in the blood may increase. The effect of this is not known.
 
Rifampin (Rifadin, Rimactane)
Taking rifampin and zolpidem together may cause your body to metabolize the medicines differently than intended. Your healthcare provider may choose to adjust your dose accordingly.
 
Flumazenil (Romazicon)
Taking both zolpidem and flumazenil may cause the sedative effect of zolpidem to be reversed. If you are taking flumazenil, consult your healthcare provider prior to taking zolpidem.
 
Other Medicines That Act on the Brain
There are a number of medicines that act on the brain, including medications for depression and anxiety. Although there have been no specific studies on the interaction between these medicines and zolpidem, it is possible for an interaction to occur. Your healthcare provider may use caution when prescribing zolpidem with another medicine that acts on the brain.
 

Drug Interactions With Zolpidem: Summary

There are a number of medications that zolpidem can interact with. It is possible that not all zolpidem drug interactions were discussed is this article. Therefore, you should talk with your doctor about the specific drug interactions that may apply to you.
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;